Genes
Oligo Pools
NGS
Variant Libraries
Antibodies
IVDR Solutions
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Reliable, scalable genomic library enrichment
This solution provides standardized conditions for specific binding across diverse panels, eliminating the need for complex optimization and supporting uniform coverage even for challenging, GC-rich samples.
Achieve excellent capture uniformity
Balanced coverage and high on-target rates minimize sequencing waste and lower total project costs.
Standardize workflows without optimization
Simplify laboratory operations with a versatile system for fixed, custom, or spike-in genomic content.
Amplify challenging targets with confidence
High-fidelity polymerase maintains visibility of complex regions and minimizes bias for accurate variant calling, even from low inputs.
Product Data
Coverage obtained with Twist Core Exome (top panels) and coverage with the Twist Core Exome + exon spike-ins. Both conditions provided optimal coverage without changes to the hybridization conditions using the standard Hybridization and Wash Kit.
Even coverage throughout the target results in the most cost-efficient sequencing and can increase sequencing throughput with higher multiplexing capabilities. Or use this extra sequencing flow cell space to get greater depth on the same number of samples.
Video
Optimized out of the box
Coverage obtained with Twist Core Exome (top panels) and coverage with the Twist Core Exome + exon spike-ins. Both conditions provided optimal coverage without changes to the hybridization conditions using the standard Hybridization and Wash Kit.
Maximize sequencing efficiency with even coverage
Even coverage throughout the target results in the most cost-efficient sequencing and can increase sequencing throughput with higher multiplexing capabilities. Or use this extra sequencing flow cell space to get greater depth on the same number of samples.
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Optimized out of the box
Coverage obtained with Twist Core Exome (top panels) and coverage with the Twist Core Exome + exon spike-ins. Both conditions provided optimal coverage without changes to the hybridization conditions using the standard Hybridization and Wash Kit.
Maximize sequencing efficiency with even coverage
Even coverage throughout the target results in the most cost-efficient sequencing and can increase sequencing throughput with higher multiplexing capabilities. Or use this extra sequencing flow cell space to get greater depth on the same number of samples.
